5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia

BACKGROUND: Alzheimer's disease (AD) pathology shows characteristic 'plaques' rich in amyloid beta (Aβ) peptide deposits. Inflammatory process-related proteins such as pro-inflammatory cytokines have been detected in AD brain suggesting that an inflammatory immune reaction also plays...

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Bibliographische Detailangaben
Hauptverfasser: Ayasolla, Kamesh R, Giri, Shailendra, Singh, Avtar K, Singh, Inderjit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262754/
https://ncbi.nlm.nih.gov/pubmed/16174294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-2-21
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