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Endonucleolytic processing of covalent protein-linked double-strand breaks

DNA double-strand breaks (DSBs) with protein covalently attached to 5′ strand termini are formed by Spo11 to initiate meiotic recombination1,2. The Spo11 protein must be removed for the DSB to be repaired, but the mechanism for removal has been unclear3. We show here that meiotic DSBs in budding yea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Neale, Matthew J., Pan, Jing, Keeney, Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262668/
https://ncbi.nlm.nih.gov/pubmed/16107854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03872
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