Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α

Signal transducers and activators of transcription (STATs) reside in a latent state in the cytoplasm of the cell, but accumulate in the nucleus in response to cytokines or growth factors. Localization in the nucleus occurs following STAT tyrosine phosphorylation and dimerization. In this report we d...

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Publicado en:	EMBO J
Autores principales:	McBride, Kevin M., Banninger, Gregg, McDonald, Christine, Reich, Nancy C.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2002
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1754
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