Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
Soluble karyopherins of the importin-β (impβ) family use RanGTP to transport cargos directionally through the nuclear pore complex (NPC). Whether impβ or RanGTP regulate the permeability of the NPC itself has been unknown. In this study, we identify a stable pool of impβ at the NPC. A subpopulation...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2015-03-01
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| Colección: | eLife |
| Materias: | |
| Acceso en línea: | https://elifesciences.org/articles/04052 |
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