The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

Activins, members of the transforming growth factor-β family, are pleiotropic growth and differentiation factors. Activin A induces B-cell apoptosis. To identify the genes responsible for activin-induced apoptosis, we performed retrovirus-mediated gene trap screening in a mouse B-cell line. We ident...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Yamakawa, Norio, Tsuchida, Kunihiro, Sugino, Hiromu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1684
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