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The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors

Activins, members of the transforming growth factor-β family, are pleiotropic growth and differentiation factors. Activin A induces B-cell apoptosis. To identify the genes responsible for activin-induced apoptosis, we performed retrovirus-mediated gene trap screening in a mouse B-cell line. We ident...

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Detalhes bibliográficos
Main Authors: Yamakawa, Norio, Tsuchida, Kunihiro, Sugino, Hiromu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125939/
https://ncbi.nlm.nih.gov/pubmed/11927552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1684
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