Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling

Antigenic stimulation of the B-cell receptor (BCR) is a central event in the immune response. In contrast, antigen bound to IgG negatively regulates signals from the BCR by cross-linking it to the inhibitory receptor FcγRIIB. Here we show that upon cross-linking of BCR or BCR with FcγRIIB, the rasGA...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Yamanashi, Yuji, Tamura, Toshiki, Kanamori, Toshihide, Yamane, Hidehiro, Nariuchi, Hideo, Yamamoto, Tadashi, Baltimore, David
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2000
Предметы:
Research Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC316343/
https://ncbi.nlm.nih.gov/pubmed/10640270
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы