Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling

Antigenic stimulation of the B-cell receptor (BCR) is a central event in the immune response. In contrast, antigen bound to IgG negatively regulates signals from the BCR by cross-linking it to the inhibitory receptor FcγRIIB. Here we show that upon cross-linking of BCR or BCR with FcγRIIB, the rasGA...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Yamanashi, Yuji, Tamura, Toshiki, Kanamori, Toshihide, Yamane, Hidehiro, Nariuchi, Hideo, Yamamoto, Tadashi, Baltimore, David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2000
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10640270/
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!