Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling
Antigenic stimulation of the B-cell receptor (BCR) is a central event in the immune response. In contrast, antigen bound to IgG negatively regulates signals from the BCR by cross-linking it to the inhibitory receptor FcγRIIB. Here we show that upon cross-linking of BCR or BCR with FcγRIIB, the rasGA...
Zapisane w:
| Wydane w: | Genes Dev |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10640270/ |
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