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Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein
The human cytomegalovirus gene products US2 and US11 induce proteasomal degradation of MHC class I heavy chains. We have generated an enhanced green fluorescent protein–class I heavy chain (EGFP–HC) chimeric molecule to study its dislocation and degradation in US2- and US11-expressing cells. The EGF...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125905/ https://ncbi.nlm.nih.gov/pubmed/11867532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1041 |
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