Calcineurin is essential for survival during membrane stress in Candida albicans
The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase calcineurin and block T-cell activation and transplant rejection. Calcineurin is conserved in microorganisms and plays a general role in stress survival. CsA and FK506 are toxic to several fungi, but the common huma...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11847103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.4.546 |
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