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Calcineurin is essential for survival during membrane stress in Candida albicans
The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase calcineurin and block T-cell activation and transplant rejection. Calcineurin is conserved in microorganisms and plays a general role in stress survival. CsA and FK506 are toxic to several fungi, but the common huma...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125859/ https://ncbi.nlm.nih.gov/pubmed/11847103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.546 |
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