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IL-7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors

Mice that lack the transcription factors encoded by the E2A gene or the receptor for interleukin 7 (IL-7R) have severe overlapping defects in lymphocyte development. Here, we show that E2A proteins are required for the survival of early T-lineage cells; however, they function through a pathway that...

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Bibliografische gegevens
Hoofdauteurs: Kee, Barbara L., Bain, Gretchen, Murre, Cornelis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125811/
https://ncbi.nlm.nih.gov/pubmed/11782430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.1.103
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