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IL-7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors
Mice that lack the transcription factors encoded by the E2A gene or the receptor for interleukin 7 (IL-7R) have severe overlapping defects in lymphocyte development. Here, we show that E2A proteins are required for the survival of early T-lineage cells; however, they function through a pathway that...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125811/ https://ncbi.nlm.nih.gov/pubmed/11782430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.1.103 |
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