Stepwise activation of the immunoglobulin µ heavy chain gene locus
The immunoglobulin heavy chain (IgH) gene locus spans several megabases. We show that IgH activation during B-cell differentiation, as measured by histone acetylation, occurs in discrete, independently regulated domains. Initially, a 120 kb domain of germline DNA is hyperacetylated, that extends fro...
Salvato in:
| Pubblicato in: | EMBO J |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2001
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6394 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|