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Stepwise activation of the immunoglobulin µ heavy chain gene locus
The immunoglobulin heavy chain (IgH) gene locus spans several megabases. We show that IgH activation during B-cell differentiation, as measured by histone acetylation, occurs in discrete, independently regulated domains. Initially, a 120 kb domain of germline DNA is hyperacetylated, that extends fro...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125735/ https://ncbi.nlm.nih.gov/pubmed/11707410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6394 |
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