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Exploration of the pore structure of a peptide-gated Na(+)channel

The FMRF-amide-activated sodium channel (FaNaC), a member of the ENaC/Degenerin family, is a homotetramer, each subunit containing two transmembrane segments. We changed independently every residue of the first transmembrane segment (TM1) into a cysteine and tested each position’s accessibility to t...

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Detalhes bibliográficos
Main Authors: Poët, Mallorie, Tauc, Michel, Lingueglia, Eric, Cance, Peggy, Poujeol, Philippe, Lazdunski, Michel, Counillon, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125683/
https://ncbi.nlm.nih.gov/pubmed/11598003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5595
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