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Exploration of the pore structure of a peptide-gated Na(+)channel

The FMRF-amide-activated sodium channel (FaNaC), a member of the ENaC/Degenerin family, is a homotetramer, each subunit containing two transmembrane segments. We changed independently every residue of the first transmembrane segment (TM1) into a cysteine and tested each position’s accessibility to t...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Poët, Mallorie, Tauc, Michel, Lingueglia, Eric, Cance, Peggy, Poujeol, Philippe, Lazdunski, Michel, Counillon, Laurent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598003/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.20.5595
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