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Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei

Inositol acylation is an obligatory step in glycosylphosphatidylinositol (GPI) biosynthesis whereas mature GPI anchors often lack this modification. The GPI anchors of Trypanosoma brucei variant surface glycoproteins (VSGs) undergo rounds of inositol acylation and deacylation during GPI biosynthesis...

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Bibliografiske detaljer
Main Authors: Güther, Maria Lucia Sampaio, Leal, Simone, Morrice, Nicholas A., Cross, George A.M., Ferguson, Michael A.J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125599/
https://ncbi.nlm.nih.gov/pubmed/11532956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4923
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