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Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Sampaio Guther, Maria Lucia, Prescott, Alan R., Kuettel, Sabine, Tinti, Michele, Ferguson, Michael A. J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909634/
https://ncbi.nlm.nih.gov/pubmed/33592041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009132
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