Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Sampaio Guther, Maria Lucia, Prescott, Alan R., Kuettel, Sabine, Tinti, Michele, Ferguson, Michael A. J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909634/
https://ncbi.nlm.nih.gov/pubmed/33592041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009132
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