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Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Sampaio Guther, Maria Lucia, Prescott, Alan R., Kuettel, Sabine, Tinti, Michele, Ferguson, Michael A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909634/
https://ncbi.nlm.nih.gov/pubmed/33592041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009132
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