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Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei

Inositol acylation is an obligatory step in glycosylphosphatidylinositol (GPI) biosynthesis whereas mature GPI anchors often lack this modification. The GPI anchors of Trypanosoma brucei variant surface glycoproteins (VSGs) undergo rounds of inositol acylation and deacylation during GPI biosynthesis...

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Detalhes bibliográficos
Main Authors: Güther, Maria Lucia Sampaio, Leal, Simone, Morrice, Nicholas A., Cross, George A.M., Ferguson, Michael A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125599/
https://ncbi.nlm.nih.gov/pubmed/11532956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4923
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