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Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei

Inositol acylation is an obligatory step in glycosylphosphatidylinositol (GPI) biosynthesis whereas mature GPI anchors often lack this modification. The GPI anchors of Trypanosoma brucei variant surface glycoproteins (VSGs) undergo rounds of inositol acylation and deacylation during GPI biosynthesis...

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Autors principals: Güther, Maria Lucia Sampaio, Leal, Simone, Morrice, Nicholas A., Cross, George A.M., Ferguson, Michael A.J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125599/
https://ncbi.nlm.nih.gov/pubmed/11532956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4923
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