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Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase

The protozoan parasite Trypanosoma brucei is the causative agent of the cattle disease Nagana and human African sleeping sickness. Glycoproteins play key roles in the parasite’s survival and infectivity, and the de novo biosyntheses of the sugar nucleotides UDP-galactose (UDP-Gal), UDP-N-acetylgluco...

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Detalhes bibliográficos
Main Authors: Mariño, Karina, Güther, Maria Lucia Sampaio, Wernimont, Amy K, Amani, Mernhaz, Hui, Raymond, Ferguson, Michael AJ
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270307/
https://ncbi.nlm.nih.gov/pubmed/20724435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwq115
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