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Characterization, Localization, Essentiality, and High-Resolution Crystal Structure of Glucosamine 6-Phosphate N-Acetyltransferase from Trypanosoma brucei

A gene predicted to encode Trypanosoma brucei glucosamine 6-phosphate N-acetyltransferase (TbGNA1; EC 2.3.1.4) was cloned and expressed in Escherichia coli. The recombinant protein was enzymatically active, and its high-resolution crystal structure was obtained at 1.86 Å. Endogenous TbGNA1 protein w...

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Detalhes bibliográficos
Main Authors: Mariño, Karina, Güther, M. Lucia Sampaio, Wernimont, Amy K., Qiu, Wei, Hui, Raymond, Ferguson, Michael A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147419/
https://ncbi.nlm.nih.gov/pubmed/21531872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05025-11
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