Wobble modification defect in tRNA disturbs codon–anticodon interaction in a mitochondrial disease
We previously showed that in mitochondrial tRNA(Lys) with an A8344G mutation responsible for myoclonus epilepsy associated with ragged-red fibers (MERRF), a subgroup of mitochondrial encephalomyopathic diseases, the normally modified wobble base (a 2-thiouridine derivative) remains unmodified. Since...
保存先:
| 出版年: | EMBO J |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.17.4794 |
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