T-loop phosphorylation stabilizes the CDK7–cyclin H–MAT1 complex in vivo and regulates its CTD kinase activity
Cyclin-dependent kinase (CDK)7–cyclin H, the CDK-activating kinase (CAK) and TFIIH-associated kinase in metazoans can be activated in vitro through T-loop phosphorylation or binding to the RING finger protein MAT1. Although the two mechanisms can operate independently, we show that in a physiologica...
Sábháilte in:
| Foilsithe in: | EMBO J |
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| Príomhchruthaitheoirí: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Nature Publishing Group
2001
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.14.3749 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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