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p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

Tumor suppressor p53 induction in response to cellular stresses activates the mitogen-activated protein kinase (MAPK) cascade through pathways involving Ras and Raf. p53’s ability to activate this pathway is dependent on p53-mediated transcription. In order to investigate potential p53 target gene(s...

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Bibliografiske detaljer
Main Authors: Fang, Li, Li, Guangnan, Liu, Guizhong, Lee, Sam W., Aaronson, Stuart A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125417/
https://ncbi.nlm.nih.gov/pubmed/11296226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.8.1931
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