p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

Tumor suppressor p53 induction in response to cellular stresses activates the mitogen-activated protein kinase (MAPK) cascade through pathways involving Ras and Raf. p53’s ability to activate this pathway is dependent on p53-mediated transcription. In order to investigate potential p53 target gene(s...

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Pubblicato in:	EMBO J
Autori principali:	Fang, Li, Li, Guangnan, Liu, Guizhong, Lee, Sam W., Aaronson, Stuart A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.8.1931
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