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p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades
Tumor suppressor p53 induction in response to cellular stresses activates the mitogen-activated protein kinase (MAPK) cascade through pathways involving Ras and Raf. p53’s ability to activate this pathway is dependent on p53-mediated transcription. In order to investigate potential p53 target gene(s...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125417/ https://ncbi.nlm.nih.gov/pubmed/11296226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.8.1931 |
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