FANCE: the link between Fanconi anaemia complex assembly and activity

The Fanconi anaemia (FA) nuclear complex (composed of the FA proteins A, C, G and F) is essential for protection against chromosome breakage. It activates the downstream protein FANCD2 by monoubiquitylation; this then forges an association with the BRCA1 protein at sites of DNA damage. Here we show...

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Detalhes bibliográficos
Main Authors: Pace, Paul, Johnson, Mark, Tan, Wu Meng, Mosedale, Georgina, Sng, Chelvin, Hoatlin, Maureen, de Winter, Johan, Joenje, Hans, Gergely, Fanni, Patel, K.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125396/
https://ncbi.nlm.nih.gov/pubmed/12093742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf355
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