A carregar...
The Ca(2+) concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
The mechanism of action of the anti-apoptotic oncogene Bcl-2 is still largely obscure. We have recently shown that the overexpression of Bcl-2 in HeLa cells reduces the Ca(2+) concentration in the endoplasmic reticulum ([Ca(2+)](er)) by increasing the passive Ca(2+) leak from the organelle. To inves...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125256/ https://ncbi.nlm.nih.gov/pubmed/11387204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2690 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|