Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
The Dnmt3a DNA methyltransferase is essential for mammalian development and is responsible for the generation of genomic methylation patterns, which lead to transcriptional silencing. Here, we show that Dnmt3a associates with RP58, a DNA-binding transcriptional repressor protein found at transcripti...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11350943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.10.2536 |
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