Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

The Dnmt3a DNA methyltransferase is essential for mammalian development and is responsible for the generation of genomic methylation patterns, which lead to transcriptional silencing. Here, we show that Dnmt3a associates with RP58, a DNA-binding transcriptional repressor protein found at transcripti...

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Pubblicato in:	EMBO J
Autori principali:	Fuks, François, Burgers, Wendy A., Godin, Nadia, Kasai, Masataka, Kouzarides, Tony
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11350943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.10.2536
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