Chargement en cours...
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
The Dnmt3a DNA methyltransferase is essential for mammalian development and is responsible for the generation of genomic methylation patterns, which lead to transcriptional silencing. Here, we show that Dnmt3a associates with RP58, a DNA-binding transcriptional repressor protein found at transcripti...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2001
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125250/ https://ncbi.nlm.nih.gov/pubmed/11350943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2536 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|