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Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity

DNMT3L is a regulator of imprint establishment of normally methylated maternal genomic sequences. DNMT3L shows high similarity to the de novo DNA methyltransferases, DNMT3A and DNMT3B, however, the amino acid residues needed for DNA cytosine methyltransferase activity have been lost from the DNMT3L...

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Bibliografiske detaljer
Main Authors: Aapola, Ulla, Liiv, Ingrid, Peterson, Pärt
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134241/
https://ncbi.nlm.nih.gov/pubmed/12177302
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