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Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity

DNMT3L is a regulator of imprint establishment of normally methylated maternal genomic sequences. DNMT3L shows high similarity to the de novo DNA methyltransferases, DNMT3A and DNMT3B, however, the amino acid residues needed for DNA cytosine methyltransferase activity have been lost from the DNMT3L...

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Hlavní autoři: Aapola, Ulla, Liiv, Ingrid, Peterson, Pärt
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC134241/
https://ncbi.nlm.nih.gov/pubmed/12177302
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