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Allosteric interactions between GB1 andGB2 subunits are required for optimalGABAB receptor function
Recent studies on G-protein-coupled receptors revealed that they can dimerize. However, the role of each subunit in the activation process remains unclear. The γ-amino-n-butyric acid type B (GABA(B)) receptor is comprised of two subunits: GB1 and GB2. Both consist of an extracellular domain (ECD) an...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125244/ https://ncbi.nlm.nih.gov/pubmed/11331581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.9.2152 |
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