In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds
The GABAB receptor (GABAB-R) is a heterodimeric class C G protein-coupled receptor comprised of the GABAB1a/b and GABAB2 subunits. The endogenous orthosteric agonist γ-amino-butyric acid (GABA) binds within the extracellular Venus flytrap (VFT) domain of the GABAB1a/b subunit. The receptor is...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2019-03-01
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| Serie: | Molecules |
| Soggetti: | |
| Accesso online: | http://www.mdpi.com/1420-3049/24/5/935 |
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