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Presence of GABAB Receptors Forming Heterodimers With GABAB1 and GABAB2 Subunits in Human Lower Esophageal Sphincter

Baclofen, a GABAB-receptor (GABABR) agonist has been proposed to be useful as therapeutic agent for the management of gastro-esophageal reflux disease, but whether the compound acts directly at the lower esophageal sphincter (LES) remains to be elucidated. We performed the present study to assess th...

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Hlavní autoři: Yasuhiro Torashima, Yasuhito Uezono, Masato Kanaide, Yuko Ando, Akihito Enjoji, Takashi Kanematsu, Kohtaro Taniyama
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2009-01-01
Edice:Journal of Pharmacological Sciences
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1347861319310916
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