Graded contribution of the Gβγ binding domains to GIRK channel activation
G protein coupled inwardly rectifying K(+) channels (GIRK/Kir3.x) are mainly activated by a direct interaction with Gβγ subunits, released upon the activation of inhibitory neurotransmitter receptors. Although Gβγ binding domains on all four subunits have been found, the relative contribution of eac...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12124401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162346199 |
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