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Graded contribution of the Gβγ binding domains to GIRK channel activation

G protein coupled inwardly rectifying K(+) channels (GIRK/Kir3.x) are mainly activated by a direct interaction with Gβγ subunits, released upon the activation of inhibitory neurotransmitter receptors. Although Gβγ binding domains on all four subunits have been found, the relative contribution of eac...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Sadja, Rona, Alagem, Noga, Reuveny, Eitan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 2002
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12124401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162346199
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