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Graded contribution of the Gβγ binding domains to GIRK channel activation

G protein coupled inwardly rectifying K(+) channels (GIRK/Kir3.x) are mainly activated by a direct interaction with Gβγ subunits, released upon the activation of inhibitory neurotransmitter receptors. Although Gβγ binding domains on all four subunits have been found, the relative contribution of eac...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sadja, Rona, Alagem, Noga, Reuveny, Eitan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2002
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12124401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162346199
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