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Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores

Membrane permeability barriers are among the factors contributing to the intrinsic resistance of bacteria to antibiotics. We have been able to resolve single ampicillin molecules moving through a channel of the general bacterial porin, OmpF (outer membrane protein F), believed to be the principal pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nestorovich, Ekaterina M., Danelon, Christophe, Winterhalter, Mathias, Bezrukov, Sergey M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125017/
https://ncbi.nlm.nih.gov/pubmed/12119404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152206799
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