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Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores

Membrane permeability barriers are among the factors contributing to the intrinsic resistance of bacteria to antibiotics. We have been able to resolve single ampicillin molecules moving through a channel of the general bacterial porin, OmpF (outer membrane protein F), believed to be the principal pa...

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Detalhes bibliográficos
Main Authors: Nestorovich, Ekaterina M., Danelon, Christophe, Winterhalter, Mathias, Bezrukov, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125017/
https://ncbi.nlm.nih.gov/pubmed/12119404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152206799
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