Anticonvulsant activity of a nonpeptide galanin receptor agonist

Galanin is a neuropeptide with a wide variety of biological functions, including that of a strong endogenous anticonvulsant. No nonpeptide ligands, capable of activating galanin receptors, are available today. Based on known pharmacophores of galanin, a combinatorial library was designed, synthesize...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Saar, Külliki, Mazarati, Andrey M., Mahlapuu, Riina, Hallnemo, Gerd, Soomets, Ursel, Kilk, Kalle, Hellberg, Sven, Pooga, Margus, Tolf, Bo-Ragnar, Shi, Tiejun S., Hökfelt, Tomas, Wasterlain, Claude, Bartfai, Tamas, Langel, Ülo
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2002
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12011470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102163499
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