Anticonvulsant activity of a nonpeptide galanin receptor agonist
Galanin is a neuropeptide with a wide variety of biological functions, including that of a strong endogenous anticonvulsant. No nonpeptide ligands, capable of activating galanin receptors, are available today. Based on known pharmacophores of galanin, a combinatorial library was designed, synthesize...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12011470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102163499 |
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