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Anticonvulsant activity of a nonpeptide galanin receptor agonist
Galanin is a neuropeptide with a wide variety of biological functions, including that of a strong endogenous anticonvulsant. No nonpeptide ligands, capable of activating galanin receptors, are available today. Based on known pharmacophores of galanin, a combinatorial library was designed, synthesize...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124541/ https://ncbi.nlm.nih.gov/pubmed/12011470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102163499 |
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