The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen

The three proteins that comprise anthrax toxin, edema factor (EF), lethal factor (LF), and protective antigen (PA), assemble at the mammalian cell surface into toxic complexes. After binding to its receptor, PA is proteolytically activated, yielding a carboxyl-terminal 63-kDa fragment (PA(63)) that...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mogridge, Jeremy, Cunningham, Kristina, Lacy, D. Borden, Mourez, Michael, Collier, R. John
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052160199
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!