The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen
The three proteins that comprise anthrax toxin, edema factor (EF), lethal factor (LF), and protective antigen (PA), assemble at the mammalian cell surface into toxic complexes. After binding to its receptor, PA is proteolytically activated, yielding a carboxyl-terminal 63-kDa fragment (PA(63)) that...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052160199 |
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