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Negative selection of thymocytes expressing the D10 TCR

We have analyzed the patterns of positive and negative selection of thymocytes expressing the T cell antigen receptor (TCR) from the D10.G4.1 T cell clone. This TCR confers reactivity to several non-self MHC class II alleles with a remarkably broad range of avidities. Therefore, negative selection c...

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Autors principals: Sant'Angelo, Derek B., Janeway, Charles A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124506/
https://ncbi.nlm.nih.gov/pubmed/12011450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102182499
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