Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

The long-term effect of exposure to DNA alkylating agents is entwined with the cell's genetic capacity for DNA repair and appropriate DNA damage responses. A unique combination of environmental exposure and deficiency in these responses can lead to genomic instability; this “gene–environment interac...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sobol, Robert W., Watson, David E., Nakamura, Jun, Yakes, F. Michael, Hou, Esther, Horton, Julie K., Ladapo, Joseph, Van Houten, Bennett, Swenberg, James A., Tindall, Kenneth R., Samson, Leona D., Wilson, Samuel H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092662499
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