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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress
The long-term effect of exposure to DNA alkylating agents is entwined with the cell's genetic capacity for DNA repair and appropriate DNA damage responses. A unique combination of environmental exposure and deficiency in these responses can lead to genomic instability; this “gene–environment in...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124494/ https://ncbi.nlm.nih.gov/pubmed/11983862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092662499 |
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